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BPC-157 promotes the activation of ERK1/2 in endothelial cells To evaluate the effect of BPC-157 on intracellular signal transduction, the phosphorylation levels of ERK1/2, JNK, and p38 mitogen-activated protein kinase (MAPK) were examined in HUVECs

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This suggests that after H 2 O 2 induction, FOXO4 facilitated Leydig cell senescence while maintaining the viability of senescent cells by repressing their apoptotic response

For example, we did not measure swim speed and distance measurements, as alterations of locomotion could be responsible for differences in escape latency